Day 1: Rome (Civitavecchia), Italy

Day 2: Sicily (Messina), Italy

Located in northeastern Sicily on the slopes of the Peloritani Mountains, Messina is an ancient place with a fascinating history. Walk by the ruins of the Santa Maria Alemanna Church, built in 1220 A.D. You'll also want to see the Duomo, a Romanesque and Norman cathedral that includes a display of artifacts in its treasury.

Day 3: At Sea - Cruising

Day 4: Santorini, Greece

Here on the island of Santorini, you’ll find a classic Greek seascape—whitewashed houses accented by sea-blue roofs. This is a treasure trove for both professional and amateur archeology buffs, with sites that include tombs that date back to the 9th century and the sanctuary of Apollo. In many ways, Santorini could be considered an explosive place, being that its terraced collection of homes and windmills lie on a caldera-- a huge basin formed by an erupting volcano. The island’s volcanic past has also produced delicious grapes for excellent wines that are well worth investigating while on your Santorini cruise. Some of the best on the island can be found in Pyrgos, Megalochori, and Oia. Oia’s hilltop not only has the ancient, Minoan site of Akrotiri, but is quite possibly the best vantage point from which to witness the spectacular sunsets. And, if you have some time, take a short trip to the island of Nea Kameni for a dip in its famous hot springs. The warm dark waters are enriched with iron and manganese and considered therapeutic.

Day 5: Mykonos, Greece

Mykonos is known for its whitewashed villages sprinkled with blue and jade green. It's also famous for its sophisticated nightlife. The most popular island in the Cyclades is bustling with activity, awash in beautiful alleyways, and home to alluring sandy beaches.

Days 6 & 7: Istanbul, Turkey

In exotic Istanbul, you could spend an entire day strolling through the Grand Bazaar, exploring the famous Blue Mosque, or wandering through the majestic Topkapi Palace, with its gardens, libraries and 400-roomharem.

Day 8: Ephesus (Kusadasi), Turkey

Once the capital of the Roman province of Asia Minor, this coastal town is now an archeologist’s dream. The UNESCO World Heritage ruins of Ephesus impress even those familiar with the world's other ancient cities. Though excavations have been underway for 150 years, only 20 percent of the city has been uncovered. This former Greek banking and trading center is rich with historic sites, including the Great Theater, the Temple of Hadrian, and the Temple of Artemis, one of the Seven Wonders of the Ancient World. On your Europe cruise, check out the the Celsus Library — built in 117 A.D.— made up of towering columns highlighted by the statue of the goddess of wisdom.

Day 9: Athens (Piraeus), Greece

Athens brought the world drama, history, poetry, and philosophy. Once home to the world's most powerful and civilized empires, Athens is now the world's foremost archaeological playground. The towering columns of the Parthenon still stand in homage to the virgin goddess Athena. The Parthenon sits atop the Athenian Acropolis and watches over the city where it can be seen from just about anywhere in Athens. Make it a point to visit the incredible Acropolis Museum on your cruise to Athens. The joint effort between two architects, one American and the other Greek, this outstanding building was completed and opened to the public in 2009. It focuses primarily on the Greek period dating to 5 B.C., considered to be the apex of art, culture, and philosophy in ancient Greece, but it also has artifacts from the Bronze, Roman, and Byzantine Ages. There’s even a Plexiglas walkway from which an excavated section of an old Athenian neighborhood can be viewed. In addition to an abundance of historical riches, modern Athens has plenty on offer—from scenic beaches to restaurants with superb Mediterranean cuisine and bustling central markets.

Day 10: At Sea - Cruising

While at sea, take the time to recharge before the next adventure. Lounge by the pool, be spoiled at the spa, taste the delicacies or explore the venues on-board, until we arrive at the next amazing destination.

Day 11: Naples, Italy

Framed by Mount Vesuvius along a dramatic skyline, the 2,800 year-old port city of Naples is chock full of historical sites, churches, and museums that make it a fascinating place for you to explore. For all of Rome’s notoriety and reputation, Naples, with its historic city center deemed a UNESCO World Heritage Site, has just as many important archeological sites and landmarks. Visit the Museo Archeologico Nazionale for a world-class collection of Egyptian and Graeco-Roman artifacts. And, if you’d like to venture a little deeper on your Naples cruise, then exploring Naples from below the ground is a must. Start with a trip into the basement of the San Lorenzo Maggiore church where you’ll find a partially excavated Roman market and a little deeper, just below the Roman ruins, you’ll find remnants from the Greeks to discover. And in the region where pizza was first invented, you know the food is going to be incredible. Whether you’re looking for a thin, wood-fired Margherita pie, spaghetti alle vongole or a zeppole dusted with confectioner’s sugar, Naples and her bountiful edible treasures is sure to please. Only 35 miles down the coast, Salerno offers you a rich history, but also boasts a marvelous collection of parks, natural wonders, and unique vantage points to take in the beauty of the Tyrrhenian Sea. Two cities. One incredible stretch of Italian coastline.

Day 12: Rome (Civitavecchia), Italy